Studies on monoamine oxidase (IV): Monoamine oxidase activity in the rat brain and estrous cycle
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چکیده
منابع مشابه
Studies on monoamine oxidase. (Report XXV). Effects of alcohols on beef liver mitochondrial monoamine oxidase.
The effects of alcohols on MAO activity in beef and rat liver mitochondria were studied. MAO activity was determined manometrically using tyramine (1× 10-2 M) as substrate and expressed as O2 uptake in 60 min. At concentrations of 0.1 to 10%, methanol and ethanol increased MAO activity in both beef and rat liver mitochondria. Activation of MAO by ethanol was reversib...
متن کاملFluctuations in Monoamine Oxidase Activity in the Hypothalamus of Rat during the Estrous Cycle and after Castration.
It now seems reasonable to postulate that in the hypothalamus there exists a mechanism that is peculiarly concerned with the release of ovulating hormone and through which changes in the external environment and in the ovarian hormones may influence pituitary function. Markee et al. (1948) produced ovulation by instilling epinephrine directly into the pars distalis or into the third ventricle. ...
متن کاملMonoamine Oxidase. Iv. Nature of the Second Prosthetic Group of Plasma Monoamine Oxidase.
Previous papers in this series have described the crystallization and preliminary characterization of beef plasma monoamine oxidase (1) as well as the fact that cupric copper is one of the prosthetic groups of this enzyme (2). In the present paper, studies related to the second prosthetic groups of this enzyme are presented and the results discussed. A preliminary report has already been publis...
متن کاملBrain and skeletal muscle monoamine oxidase activity in schizophrenia.
Monoamine oxidase (MAO) activity has been studied in postmortem brain specimens from chronic schizophrenics and comparison groups by various laboratories. There is no evidence for decreased MAO activity in the brains of the schizophrenic patients, but many possible sources of error in postmortem studies make the conclusions of these studies less than definitive. However, since almost complete i...
متن کاملMonoamine oxidase: radiotracer development and human studies.
Monoamine oxidase (MAO) is an integral protein of outer mitochondrial membranes and occurs in neuronal and nonneuronal cells in the brain and in peripheral organs. It oxidizes amines from both endogenous and exogenous sources, thereby influencing the concentration of neurotransmitter amines as well as many xenobiotics. It occurs in two subtypes, MAO A and MAO B, which are different gene product...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1978
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)67302-6